Cryo-Fixation SEM Imaging Service Based on Leica Cryo CLEM System

STEMart offers advanced Cryo-Fixation Scanning Electron Microscopy (SEM) Imaging Services using the Leica Cryo CLEM System. This powerful technology is essential for high-resolution imaging of biological samples preserved in their near-native state. By utilizing cryo-fixation, we ensure that delicate cellular structures and biological materials are maintained, delivering precise, artifact-free images for detailed analysis in various research and industrial applications.

The Leica Cryo CLEM System integrates cryo-fixation and electron microscopy technologies to provide high-resolution imaging of frozen biological samples. Cryo-fixation preserves the native state of samples by rapidly freezing them, preventing the formation of ice crystals that could damage delicate structures. The system allows for seamless transition between light and electron microscopy, enabling correlative studies of ultrastructures and molecular localization.

Leveraging our Leica Cryo CLEM System, STEMart offers a range of cryo-fixation SEM imaging services tailored to meet the needs of researchers across disciplines such as structural biology, cellular biology, and materials science. Our services enable detailed visualization of complex samples at ultra-high resolution, supporting advanced research and industrial projects.

What We Offer

• Cryo-SEM Imaging

Capture high-resolution images of frozen biological samples, preserving their native structures for accurate analysis without the risk of damage or artifacts.

• Correlative Cryo-Light and SEM Microscopy

Combine light and electron microscopy to study molecular localization within the context of cellular ultrastructure, delivering comprehensive insights into biological samples.

• Cryo-Fixation for Biomaterials

Provide cryo-fixation services for biomaterials, allowing detailed imaging of soft tissues, gels, and other delicate samples that require preservation of their native state.

• Subsurface Structure Analysis

Analyze subsurface structures in biological samples with cryo-fixation SEM, revealing internal features while maintaining sample integrity.

• Cryo-Lamella Preparation

Prepare thin cryo-lamella sections for high-resolution imaging and subsequent analysis using both cryo-SEM and cryo-electron microscopy.

Why Choose Us

• High-Resolution Imaging with Cryo-Preservation

Our Leica Cryo CLEM System offers the highest levels of resolution while preserving the natural state of biological samples through rapid freezing techniques.

• Expertise in Correlative Microscopy

We provide expert-level correlative microscopy services that combine both light and electron microscopy for a complete understanding of sample structure and molecular function.

• Advanced Cryo-Fixation Techniques

Benefit from our advanced cryo-fixation protocols, ensuring that even the most delicate samples are preserved for accurate imaging.

• Non-Destructive Sample Analysis

Cryo-fixation prevents damage to your sample, maintaining its structural integrity during analysis, offering non-destructive imaging solutions.

Our Equipment

Leica Cryo CLEM System

The Leica Cryo CLEM System is a cutting-edge platform designed for high-resolution cryo-fixation SEM imaging. It allows for seamless integration between cryo-light and electron microscopy, providing unmatched preservation of biological samples in their frozen state. This system enables the study of complex samples with precision, ensuring that native structures are maintained throughout the imaging process.

STEMart provides high-quality advanced microscopy services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our advanced microscopy services and how we can help you achieve your research goals.