MDSC Assays Service Based on Flow Cytometry Systems

STEMart offers specialized MDSC (Myeloid-Derived Suppressor Cells) Assays services utilizing advanced flow cytometry systems. These systems are pivotal in our laboratory, enabling precise identification and characterization of MDSC populations within complex biological samples. Their high sensitivity and multi-parametric analysis capabilities make them indispensable tools for immunological research and therapeutic development.

Flow cytometry systems operate by passing cells through a laser beam, detecting scattered light and fluorescence emissions to analyze various cellular properties. Specifically, for MDSC assays, these systems can differentiate cell populations based on surface markers and intracellular components, providing detailed insights into the immunosuppressive landscape. This technology is extensively applied in oncology, immunotherapy, and translational medicine to understand tumor-induced immunosuppression and to develop targeted therapies.

Leveraging our cutting-edge flow cytometry systems, we provide a comprehensive suite of MDSC Assays services. These services are meticulously designed to meet the specific needs of your research, ensuring accurate, reliable, and reproducible results.

What We Offer

• MDSC Phenotyping

Detailed characterization of MDSC subsets (G-MDSCs and M-MDSCs) based on surface marker expression, enabling precise identification within heterogeneous cell populations.

• Functional Suppression Assays

Assessment of MDSC immunosuppressive functions, including T-cell proliferation inhibition and cytokine production analysis, to evaluate their impact on immune responses.

• Quantitative Analysis

Accurate quantification of MDSC frequencies in various sample types, such as blood, tumor tissues, and bone marrow, facilitating comparative studies.

• Custom Panel Design

Development of tailored flow cytometry panels to target specific markers relevant to your research objectives, enhancing assay specificity and sensitivity.

Advantages of Services Using Our Flow Cytometry Systems

• High Sensitivity and Specificity

Our systems can detect low-abundance MDSC populations with high accuracy, ensuring reliable identification even in complex samples.

• Multi-Parametric Analysis

Ability to analyze multiple markers simultaneously, providing comprehensive insights into MDSC phenotypes and functions.

• Rapid Processing

High-throughput capabilities allow for the efficient analysis of large sample volumes, expediting research timelines.

• Expert Data Interpretation

Our experienced team offers in-depth analysis and interpretation of flow cytometry data, delivering actionable insights for your research.

Our Equipment

BD FACSymphony A5

A high-parameter flow cytometer enabling the analysis of up to 50 parameters simultaneously, ideal for complex MDSC phenotyping.

Cytek Aurora

A spectral flow cytometer offering exceptional resolution and sensitivity, facilitating detailed characterization of MDSC subsets.

BD LSRFortessa

Versatile flow cytometer with customizable configurations, supporting high-throughput MDSC assays with precision.

BD FACSAria Fusion

Combines high-speed cell sorting with advanced analysis capabilities, allowing for the isolation of specific MDSC populations.

STEMart provides high-quality flow cytometry services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our flow cytometry services and how we can help you achieve your research goals.