Post-Translational Modification Analysis Service Based on LC-MS/MS

STEMart offers Post-Translational Modification (PTM) Analysis Services using cutting-edge LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry), a highly sensitive and precise technique for identifying and quantifying modifications on proteins and peptides. In our laboratory, LC-MS/MS plays a critical role in providing in-depth analysis of PTMs, offering unmatched sensitivity and resolution. This powerful combination allows us to analyze complex biological samples and deliver high-quality, detailed results that support research in proteomics, cell biology, and disease studies.

LC-MS/MS operates by separating peptides using liquid chromatography before analyzing them with tandem mass spectrometry. This dual approach allows for the precise identification of peptides and their modifications, including phosphorylation, glycosylation, acetylation, and ubiquitination. The ability to identify both known and novel modifications makes LC-MS/MS an essential tool for studying protein function, signaling pathways, and disease mechanisms. The technique is widely applied in drug development, biomarker discovery, and fundamental biological research.

Leveraging our expertise in mass spectrometry and our state-of-the-art LC-MS/MS systems, STEMart offers a comprehensive range of PTM analysis services tailored to meet the needs of our clients. From routine PTM identification to in-depth characterization of complex modifications, our services provide the accurate data needed to advance your research and development projects.

What We Offer

• Phosphorylation Site Analysis

We use LC-MS/MS to identify and characterize phosphorylation sites on proteins and peptides, helping you study signaling pathways and regulatory mechanisms.

• Glycosylation Analysis

Our service provides detailed analysis of glycosylation sites, characterizing both the attached glycans and their impact on protein function.

• Acetylation and Methylation Analysis

We offer comprehensive analysis of acetylation and methylation modifications, which play key roles in gene regulation and protein stability.

• Ubiquitination and SUMOylation Analysis

Our LC-MS/MS technology enables the identification and quantification of ubiquitination and SUMOylation sites, crucial for studying protein degradation and cellular signaling.

• Custom PTM Analysis

For unique PTMs or specific research needs, we offer customized PTM analysis services tailored to your project requirements.

Why Choose Us

• High Sensitivity and Specificity

Our LC-MS/MS systems deliver high sensitivity and specificity, allowing for the accurate identification and quantification of low-abundance PTMs.

• Comprehensive PTM Coverage

We offer a wide range of PTM analyses, from phosphorylation to ubiquitination, providing a complete solution for studying protein modifications.

• Expert Team

Our team of skilled mass spectrometrists and biochemists ensures that your samples are analyzed with precision, delivering reliable and reproducible results.

• Advanced Technology

We utilize the latest LC-MS/MS technology to ensure that our clients receive the most accurate and detailed data for their research.

Our Equipment

LC-MS/MS

The backbone of our PTM analysis services, this system provides high sensitivity and resolution for the identification and quantification of post-translational modifications on proteins and peptides.

Orbitrap Exploris™ 240

A high-resolution mass spectrometer that complements our LC-MS/MS system, offering exceptional accuracy and depth of analysis for PTM studies.

Nano-LC-MS/MS

This advanced liquid chromatography system coupled with tandem mass spectrometry allows for the separation and detailed analysis of complex PTMs in biological samples.

STEMart provides high-quality mass spectrometry services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our mass spectrometry services and how we can help you achieve your research goals.