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Microfluidics for Microfiber Synthesis

Microfibers feature unique properties, such as high surface area to volume ratio, strong interfacial interactions, surface roughness and versatile surface functionalities, which make them either be used in the plain form for coating the substrates or scaffolding cell cultures or be filled with cells, medicine, and nanoparticles. Diameter of microfiber is one of the most crucial morphological parameters which determines many properties mechanical, cell adhesion and proliferation, biomimicking extracellular matrix, optical extinction capacity and filtration performance.

Traditional approaches for production of micro- and nanofiber include melt spinning, wet spinning, draw spinning, macromolecular assembly and electrospinning. While the micro- and nanofibers produced by these techniques have limitation in terms of morphology and material diversity. Microfluidic spinning provides an outstanding and simple solution for the production of micro- and nanofibers with controllable size, diverse composition morphology.

Solidification Methods for Microfibers Synthesis via Microfluidic Spinning Technology

  • Photopolymerization reaction
  • Chemical crosslinking reaction
  • Ionic crosslinking reaction
  • Solvent evaporation

STEMart can utilize microfluidics techniques to produce microfibers with complex geometry by controlling the flow conditions (such as flow rates and viscosities), types and concentrations of solution used. These high-quality microfibers can be used in tissue engineering, drug delivery and release, flexible electronics, water collection, and surgical suturing, etc.

What We Can Do for You

  • Production of microfibers with different cross-section shapes, such as circular, hollow, core-shell, T-shaped, U-shaped, E-shaped, H-shaped
  • Production of microfibers with different structure, such as straight, waves, and spirals
  • Production of microfibers with a different core material
  • Production of multi-component microfibers
  • Production of microfibers with a concentration gradient

Advantage of Microfluidic Device in Production of Microfibers

  • Controllable fiber diameter
  • Unprecedented flexibility in altering the microfiber structure
  • Diversity in material composition

For more information about our microfiber synthesis service, please contact us.

Reference

  1. Zhang, Mengfan, et al. (2022). "Recent Progress in Preparation and Application of Fibers Using Microfluidic Spinning Technology." Macromolecular chemistry and physics. 5:223.

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