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Spinal cord injury is a disease with a high disability rate, and the number of patients is increasing year by year. Establishing an ideal animal model is the basic premise for studying the disease mechanism.
As a spinal cord injury model, rats also have the following characteristics: good reproducibility; good clinical relevance; high homology with humans; strong repeatability; wide range of adaptation; simple operation; low mortality rate, etc. The spinal cord injury model is usually established by directly cutting the thoracic vertebrae of rats and compressing them with heavy objects.