Construction of Animal Disease Model

Animal disease models refer to animals with simulated performance of human diseases established in various medical scientific research. The construction of animal disease model is a very important experimental method and means in modern biomedical and pharmaceutical research. With the help of animal disease models, we can accurately observe the experimental results of the models and conduct comparative studies with human diseases, so as to more conveniently and effectively understand the occurrence and development patterns of human diseases and study prevention and treatment measures.

Preclinical research on new drugs uses animal models of human diseases to replicate drug administration, and simulates the absorption, distribution, metabolism and excretion processes of drugs in disease animals to evaluate the safety and effectiveness of drugs. Drugs with different mechanisms of action need to correspond to different animal disease models to make the experimental results more consistent with clinical practice, thereby improving the prediction accuracy of drug safety assessment and providing a theoretical basis for clinical research of drugs.

STEMart can construct appropriate animal disease models for new drugs with different mechanisms of action, covering digestive system, respiratory system, cardiovascular system, nervous system, tumor animal models, etc.

Animal Disease Model Types

• Animal models of digestive diseases
  • Gastric acid secretion model
  • Gastric ulcer model
  • Pancreatitis model
  • Liver fibrosis model
  • Fatty liver model
• Animal models of respiratory diseases
  • Pulmonary fibrosis model
  • Chronic pulmonary obstruction model
  • Acute lung injury model
  • Asthma model
  • Pulmonary embolism model
  • Bronchitis model
• Animal models of cardiovascular diseases
  • Coronary heart disease model
  • Myocardial infarction model
  • Cardiac arrest model
  • Chronic heart failure model
  • Arrhythmia model
  • Atherosclerosis model
  • Hypertension model
• Animal models of neurological diseases
  • Stroke model
  • Embolic cerebral infarction model
  • Cerebral hemorrhage model
  • Brain injury model
  • Spinal cord injury model
  • Parkinson model
  • Alzheimer's disease model
• Tumor animal models
  • Spontaneous tumor animal model
  • Induced tumor animal model
  • Tumor cell line transplantation model
  • Human tumor tissue xenotransplantation model

For more information about our animal disease model construction services, please contact us.