Pharmacokinetic Research and Evaluation

After the drug enters the body, it is absorbed into the blood, passes through the membrane with the blood flow, enters the target tissue, and binds to the receptor, thereby producing a pharmacological effect. After the effect is over, it must be eliminated from the body. Pharmacokinetic research is the quantitative analysis of the absorption, distribution, excretion and metabolism of drugs in the organism, which can predict the efficacy and toxicity of drugs, and guide the rational application and clinical treatment of drugs.

In the development process of new drugs, pharmacokinetics research is equally important as pharmacodynamics and toxicology research. Non-clinical pharmacokinetic research and evaluation uses in vitro and in vivo animal research methods to reveal the dynamic changes of drugs in the body and obtain basic pharmacokinetic parameters of drugs. It plays an important role in the evaluation process of new drug research and development.

STEMart has a strong research and development team and rich industry experience, and can provide you with professional pharmacokinetic research and evaluation services to help promote the development process of new drugs.

Test Samples

Various new drugs

Service Items

• In vivo metabolism research
  • Characterization of drug absorption, distribution, metabolism and excretion characteristics
  • Intracorporal process of drugs and major pharmacokinetic parameters
  • Bioavailability
  • Bioequivalence
• In vitro metabolism research
  • Metabolic stability in humans and animals
  • Drug metabolism interactions
  • Drug transport properties
  • Plasma protein binding
  • Metabolite analysis

For more information about our pharmacokinetic research and evaluation services, please contact us.