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Official Full Name: ADAM metallopeptidase with thrombospondin type 1 motif 13<br />Also known as: VWFCP; C9orf8; vWF-CP; ADAM-TS13; ADAMTS-13<br />This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.