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Official Full Name: aryl hydrocarbon receptor interacting protein
Also known as: ARA9; XAP2; PITA1; XAP-2; FKBP16; FKBP37; SMTPHN
The protein encoded by this gene is an aryl hydrocarbon receptor and a ligand-activated transcription factor. The encoded protein is present in the cytoplasm as part of a multiprotein complex, but is transported into the nucleus after binding to a ligand. This protein can regulate the expression of various exogenous metabolic enzymes. In addition, the encoded protein can specifically bind and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene.