Analysis of AKT3 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0795-LGZ)

Introduction

Official Full Name: AKT serine/threonine kinase 3<br />Also known as: MPPH; PKBG; MPPH2; PRKBG; STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma<br />The protein encoded by this gene is a member of AKT, also known as PKB, the serine/threonine protein kinase family. AKT kinase is thought to be a regulator of cellular signaling by insulin and growth factors. They are involved in a variety of biological processes, including cell proliferation, differentiation, apoptosis, tumorigenesis, and glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). In addition, splice transcript variants encoding different isoforms have been described.