Analysis of CD247 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0825-LGZ)

Introduction

Official Full Name: CD247 molecule
Also known as: T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3ZETA; CD3-ZETA
The protein encoded by this gene is the T-cell receptor zeta, which together with the T-cell receptor alpha/beta and gamma/delta heterodimers and CD3-gamma, -delta and -epsilon form the T-cell receptor-CD3 complex. Zeta chains play an important role in the coupling of antigen recognition to multiple signal transduction pathways in cells. Low expression of antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.