Analysis of CEACAM-7/CGM2 (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0101-LGZ)

Introduction

CEACAM-7 (Carcinoembryonic antigen-related cell adhesion molecule 7; CGM2) is a GPI-anchored glycoprotein that is preferentially expressed on the luminal surface of epithelial cells near the ostium of colonic crypts and in pancreatic ductal epithelial cells. It is downregulated during the development of colorectal adenomas but upregulated during the development of gastric cancer. CEACAM-7 binds CEACAM-1, consistent with heterotropic interactions of CEACAM-1 with other CEACAM family members.