Analysis of DDR2 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0892-LGZ)

Introduction

Official Full Name: discoidin domain receptor tyrosine kinase 2<br />Also known as: TKT; WRCN; MIG20a; NTRKR3; TYRO10<br />This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinases (RTKs) protein family. RTKs play a key role in the communication between cells and their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. The protein is expressed in many cell types and may also be involved in wound repair and regulation of tumor growth and aggressiveness. Mutations in this gene are responsible for epiphyseal dysplasia with short limbs.