Analysis of KCNK2 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1079-LGZ)

Introduction

Official Full Name: potassium two pore domain channel subfamily K member 2<br />Also known as: TREK; TPKC1; TREK1; K2p2.1; TREK-1; hTREK-1c; hTREK-1e<br />This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene.