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Official Full Name: nuclear receptor binding SET domain protein 3<br />Also known as: KMT3F; KMT3G; WHISTLE; WHSC1L1; pp14328<br />This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described.