Analysis of OLFML3 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1169-LGZ)

Introduction

Official Full Name: olfactomedin like 3<br />Also known as: OLF44; HNOEL-iso<br />This gene encodes a member of the olfactomedin-like gene family which also includes genes encoding noelin, tiarin, myocilin, amassin, optimedin, photomedin, and latrophilin. The encoded protein is a secreted extracellular matrix glycoprotein with a C-terminal olfactomedin domain that facilitates protein-protein interactions, cell adhesion, and intercellular interactions. It serves as both a scaffold protein that recruits bone morphogenetic protein 1 to its substrate chordin, and as a vascular tissue remodeler with pro-angiogenic properties. Alternative splicing results in multiple transcript variants.