Unlock Exclusive Discounts & Flash Sales! Click Here to Join the Deals on Every Wednesday!
Official Full Name: proteoglycan 4
Also known as: MSF; SZP; CACP; HAPO; JCAP
The protein encoded by this gene is a large proteoglycan synthesized by chondrocytes and some synovial lining cells that line the surface of articular cartilage. This protein contains chondroitin sulfate and keratin sulfate glycosaminoglycans. It acts as a boundary lubricant on the cartilage surface, facilitating the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.