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Official Full Name: proteoglycan 4<br />Also known as: MSF; SZP; CACP; HAPO; JCAP<br />The protein encoded by this gene is a large proteoglycan synthesized by chondrocytes and some synovial lining cells that line the surface of articular cartilage. This protein contains chondroitin sulfate and keratin sulfate glycosaminoglycans. It acts as a boundary lubricant on the cartilage surface, facilitating the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.