Analysis of Prolactin by ELISA (CAT#: STEM-MB-1531-LGZ)

Introduction

Prolactin (PRL) is a neuroendocrine pituitary hormone encoded by the PRL gene and synthesized by the pituitary, placenta, brain, uterus, dermal fibroblasts, decidua, B cells, T cells, natural killer cells, and breast cancer cells. Prolactin is low in human pregnancy in the first trimester and is replaced by placental prolactin, but increased in the third trimester. Prolactin plays an important role in metabolism, immune system regulation and pancreatic development. Prolactin also acts in a cytokine-like manner and is an important regulator of the immune system. As growth, differentiation and anti-apoptotic factors, it has important cell cycle related functions. As a growth factor that binds to cytokine-like receptors, it affects hematopoiesis, angiogenesis, and is involved in the regulation of blood coagulation through a variety of pathways.