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Official Full Name: Ras association domain family member 5
Also known as: RAPL; Maxp1; NORE1; NORE1A; NORE1B; RASSF3
This gene is a member of the Ras-association domain family. It functions as a tumor suppressor and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules and binds to the GTP-activated form of Ras, Rap1 and several other Ras-like small GTPases. This protein regulates lymphocyte adhesion and inhibits cell growth by activating Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.