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Official Full Name: regulator of G protein signaling 8<br />This gene is a member of the Regulator of G-protein Signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) is a regulatory and structural component of the G protein-coupled receptor complex. They accelerate translocation through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, they also accelerate activation of receptor stimulation.