Analysis of RHOQ Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1756-LGZ)

Introduction

Official Full Name: ras homolog family member Q<br />Also known as: ARHQ; TC10; TC10A; RASL7A; HEL-S-42<br />This gene encodes a member of the Rho family of small GTPases that cycles between inactive and active GTP-bound states and acts as a molecular switch in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton, regulating cell shape, attachment and motility. The encoded protein is an important signal protein for leiomyoma assembly, which has been shown to play an important role in the extracellular secretion of solute carrier family 2, glucose transporter member 4 and other proteins, and may be a signal to open the membrane fusion mechanism. Three associated pseudogenes were identified on chromosomes 2 and 14.