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Official Full Name: spermidine synthase
Also known as: PAPT; SPS1; SPDSY; SRML1
The polyamines putrescine, spermine, and spermidine are universal polycationic mediators of cell growth and differentiation. Spermidine synthase is one of the four enzymes in the polyamine biosynthetic pathway and is the last step in spermidine biosynthesis. The enzyme catalyzes the conversion of putrescine to spermidine with decarboxylated s-adenosylmethionine as a cofactor.