Analysis of TARBP1 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0305-LGZ)

Introduction

Official Full Name: TAR (HIV-1) RNA binding protein 1
Also known as: TRM3; TRMT3; TRP185; TRP-185
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces chromosomally integrated DNA during a replicative cycle. The transcriptional activator Tat activates HIV-1 gene expression depending on the RNA regulatory element (TAR) downstream of the transcription initiation site. This element forms a stable stem-loop structure that can bind the protein encoded by the gene or RNA polymerase II. This protein likely disengages RNA polymerase II from the TAR during transcription elongation. An alternatively spliced transcript of this gene may exist, but its full-length nature has not been determined.