Analysis of TRIM3 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-2182-LGZ)

Introduction

Official Full Name: tripartite motif containing 3<br />Also known as: BERP; HAC1; RNF22; RNF97<br />The protein encoded by this gene is a member of the trilateral motif (TRIM) family, also known as the RING-b-box-coil-coil (RBCC) subgroup. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coil region. This protein localizes to cytoplasmic filaments. It resembles a rat protein that is a specific partner in the tail region of myosin V, a class of myosins involved in organelle-targeted trafficking. This rat protein also interacts with α-actin-4. Thus, this human protein may have a role in myosin V-mediated cargo transport. Alternately spliced transcript variants encoding the same isoform have been identified.