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Beckman Coulter AU5432 Chemistry Analyzer, 6600 tests/hour In Ramsey, MN, USA (CAT#: STEM-AIPO-0219-YJL)

Cat Number: STEM-AIPO-0219-YJL

Application: Used to calculate the concentration of certain substances within samples of serum, plasma, urine and/or other body fluids

Model: AU5432

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Description

Beckman Coulter AU5432 Chemistry Analyzer, 6600 tests/hour In Ramsey, MN, USA, model AU5432, is manufactured by Beckman - Coulter general laboratory equipment.
The Beckman Coulter AU5432 Chemistry system boasts over 100 assays with a maximum throughput of 6600 tests per hour. The AU family of systems are well regarded, open reagent, high quality chemistry systems that are considered one of the most popular chemistry systems on the market, in particular in the US laboratory marketplace. Chemistry analyzers measure substances within bodily fluids to establish a pattern of abnormalities. The wide range of tests can be grouped under several categories such as electrolytes, enzymes, blood sugar, metabolites, thyroids, hormones, lipids, therapeutic drug monitoring, and drugs of abuse monitoring. This analysis can be conducted on blood (either whole, serum or plasma), urine, semen or cerebrospinal fluids Chemistry analysis begins with patient sample placed in separate capsules, test tubes, slides or sample cups that are transported on a conveyor with sample racks or in a carousel in a reagent tray. Specimens are sampled and then mixed automatically together with diluents and reagents in a reaction cuvette. The reagents are pulled from a reagent carousel, which is typically refrigerated to keep the reagents shelf life longer. The reactive cuvette is stored and processed in the Reaction carousel. The Reaction carousel holds the mixing station (which mixes samples and reagents) and wash station (which rinses the cuvettes). Dependent on the manufacturer, the cuvette is either made of glass or plastic, but must be optically clear so that light may pass through without any intervention from scratches or blemish. Chemistry analysis is calculated through the absorbance of the specific wavelengths as light is passed through the specimen. All chemistry analyzers possess a photometer (either filter photometer or spectrophotometer) that conducts the measurement of the light absorbance of the specimen, and results are calculated. Filter photometers use glass filters, on a rotating filter wheel, coated with colored material while spectrophotometers use prisms or gratings, to isolate these wavelengths from the scanner beam. In both cases, a lamp (typically halogen) is the light source. Spectrophotometry is a more commonly used method than Filter photometry, which is currently only used in J&J, Roche Cobas and Siemens Dimension systems. Spectraphometry is used in most other systems including Abbott, Beckman and Roche Hitachi systems. The process to attain the results from the absorbance tests are classified either as End Point or Kinetic. End point method incubates the reaction mixture for a predetermined amount of time to reach the end point, or equilibrium of the reaction. Kinetic method, as the reagents and the sample are mixed, the reaction is monitored, the rate of change in absorbance is then determined and related to analyte concentration. As such, Kinetic is a faster method than End Point.

Specification

Condition: Used
Analytical System: Fully automated, random access chemistry system with STAT capability
Analytical Principle: Spectrophotometry and potentiometry
Analytical Types: Endpoint, rate, fixed point and indirect ISE
Analytical Methods: Colorimetry, turbidimetry, latex agglutination, homogeneous EIA, indirect ISE
Simultaneously Processed Analytes: 60 photometric tests + 3 ISE, 120 pre-programmed onboard tests
Throughput: 400 photometric tests/hour; maximum of 800 with ISE
ISE Throughput: 200 samples/hr. Maximum tests/hr: 600 if ISE only
Sample Types: Serum, plasma, urine, other
Sample Feeder: Racks with 10 samples each (barcodes on primary tubes and on racks); capacity of 80 samples; continuous loading
Sample Tubes: Primary and secondary tubes; diameter from 11.5 to 16 mm; height from 55 to 102 mm, nestled micro sample cups
STAT samples: Up to 22 positions for STAT samples via cooled turntable. Easy-to-operate interrupts between tests. Auto-repeat run capability.
Sample Volume: 1–25 μl in 0.1 μl steps (1-25 μl for repeats)
Reagent Capacity: 76 positions for (R1+R2, detergent position). Holds 15, 30 and 60ml bottles.
Reagent Storage: Refrigerated (4–12°C)
Reagent Volume: R1: 10–250 μl; R2: 10–250 μl (in 1 μl increment)
Total Reaction Volume: 90–350 μl
Reaction Cuvette: Permanent glass cuvettes
Reaction Time: Up to 8 minutes, 37.5 seconds
Reaction Incubation: 37°C, dry bath
Photometry System: Direct assay through the reaction cuvette (0–3.0 OD) mono and bichromatic measurements possible
Wavelength: 13 different wavelengths between 340–800 nm
Calibration: Auto calibration, cooled calibrator positions; master calibration established by two-dimensional barcode
Quality Control: Auto QC, cooled QC positions
Rerun: 1. Auto rerun and manual rerun available
2. Automatic sample increase, decrease or normal repeat
3. Reflex testing
Sample Pre-dilution: Dilution ratio: Fixed to 3, 5, 10, 15, 20, 25, 50, 76 or 100
Test Requisition: Individual and profile test requisition via online, mouse, function keys and touch-screen
Sample Integrity: Lipaemia, Haemolysis and Icterus analysis. Sample clot detection and probe crash protection.
Online: RS232C. Full uni- and bidirectional communication possible.
Software: Windows 7®
Data Storage: Sample number 100,000 samples. Reaction Data 200,000 tests.
Dimensions (W x H x D): ANL: 1,450 x 1,205 x 760
Power Supply: 100–240v; 60 Hz/ < 3.5 kVA

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