Biacore 8K, Cytiva (CAT#: STEM-CTEPO-0061-ZJF)

The Biacore 8K is manufactured by Cytiva.
The Biacore 8K is a high-throughput, high-sensitivity SPR system. This unit is certified and comes with a 90-day warranty (US/Canada).
This system enables efficient screening, characterization, process optimization, and quality control of small molecules and biotherapeutics.

Condition: Refurbished, Certified pre-owned
Detection technology: Surface plasmon resonance (SPR) biosensor
Information provided: Kinetic and affinity data (ka , kd , KD), specificity, selectivity and screening data
Data presentation: Result tables, result plots, and real-time monitoring of sensorgrams
Analysis time per cycle: Typically 2 to 15 min
Automation: 60 h unattended operation
Sample type: Small molecule drug candidates to high molecular weight proteins (also DNA, RNA, polysaccharides, lipids, cells, and viruses) in various sample environments (e.g., in DMSO containing buffers, plasma, and serum)
Required sample volume: Injection volume plus 20 to 50 μL (application dependent)
Injection volume: 1 to 200 μL
Flow rate range: 1 to 100 μL/min
Flow cell volume: 40 nL
Flow cell height: 70 μm
Data collection rate: 1 or 10 Hz
Sample/reagent capacity: 4 × 96- or 384-well microplates, normal and deep-well.
Typical run time:
Clean screen (384-well plate): 1 h
Binding level screen (384-well plate): 2 h
Affinity screen (64 samples): 3 h
Kinetic analysis (64 samples): 5 h
Kinetic screen, single concentration
(384-well plate): 5.5 h
Analysis temperature range: 4°C to 40°C (maximum 20°C below ambient temperature)
Sample storage: 4°C to 40°C (maximum 18°C below ambient temperature)
Sample refractive index range: 1.33 to 1.39
In-line reference subtraction: Automatic
Number of flow cells: 16 in 8 channels
Dimensions (W × H × D): 902 × 860 × 622 mm
Net weight total: 127 kg
Mains requirements: Processing unit: Autorange voltage 100 to 240 V~, Frequency 50/60 Hz
Power consumption: Processing unit: maximum 350 VA

Single solution for interaction analysis allowing ranking, kinetics, affinity, epitope binning, concentration, and relative potency
Screens 2300 molecules in a day
High-quality kinetic characterization of 64 interactions in 4 h
High sample capacity of up to 4 × 384-well microplates
60 h unattended runtime with queueing capability and rapid multirun evaluations

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