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Characterization of Bone in the GHz Range by Brillouin Light Scattering (CAT#: STEM-ST-0129-YJL)

Introduction

Bone and cartilage are specialized forms of connective tissue that provide structural support for muscles and organs within the human body. Bone is hard, highly vascularized and calcified connective tissue that comprises the skeleton whereas cartilage is soft, flexible, avascular, tissue that serves to absorb shock in the joints between bones, or forms rigid, low-load bearing structures such as within the nose, ear and larynx. The structure and mechanical properties of bone and cartilage are integral to their function, and disruption of these properties is implicated in injury and degenerative conditions such as arthritis and osteoporosis. Earlier detection of changes in the structure and strength of bone and cartilage will facilitate earlier diagnosis, which is key to effective treatment and improved patient outcomes.




Principle

From a quantum point of view, Brillouin scattering is an interaction of light photons with acoustic or vibrational quanta (phonons), with magnetic spin waves (magnons), or with other low frequency quasiparticles interacting with light. The interaction consists of an inelastic scattering process in which a phonon or magnon is either created (Stokes process) or annihilated (anti-Stokes process). The energy of the scattered light is slightly changed, that is decreased for a Stokes process and increased for an anti-Stokes process. This shift, known as the Brillouin shift, is equal to the energy of the interacting phonon and magnon and thus Brillouin scattering can be used to measure phonon and magnon energies.

Applications

Brillouin scattering is used to determine acoustic velocities and elastic properties of a number of crystalline solids, glasses, and liquids.

Procedure

1. Sample preparation
2. Measurement by scattering detection instrument
3. Data analysis

Materials

Brillouin scattering measurement system (Brillouin spectrometer)