CMV (IE2) Peptide Pool, STEMCELL Technologies (CAT#: STEM-CT-0797-ZJF)

Stimulating T cells with CMV (IE-2) Peptide Pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. CMV (IE-2) Peptide Pool is a lyophilized mixture of 143 peptides from immediate early protein 2 (IE2) of human cytomegalovirus (CMV; strain AD169), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 - 580 on IE2. IE2 is critical for viral infection and for the expression of CMV early genes (Marchini et al.). It also controls transcription initiation for a subset of early-late and late viral promoters via RNA polymerase II (Li et al.). IE2, along with IE1, may contribute to the survival of CMV-infected cells by blocking tumor necrosis factor alpha (TNF-α)-induced apoptosis (Zhu et al.). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.

Subtype: Peptide Pools
Species: Other
Application: Activation, Cell Culture
Area of Interest: Infectious Diseases
Purity: Average 70%

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

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