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Determination of Distillation Range of Polyethylene Glycol (CAT#: STEM-PPA-0154-YJL)

Introduction

Polyethylene glycol is a high molecular polymer with a chemical formula of HO(CH2CH2O)nH, non-irritating, slightly bitter taste, good water solubility, and good compatibility with many organic components. It is widely used in various pharmaceutical formulations such as injections, topical formulations, ophthalmic formulations, oral and rectal formulations.

Solid grade polyethylene glycol can be added to liquid polyethylene glycol to adjust viscosity for topical ointment. Polyethylene glycol mixtures can be used as suppository bases. The aqueous solution of polyethylene glycol can be used as a suspending agent or used to adjust the viscosity of other suspension media. Polyethylene glycol is used in combination with other emulsifiers to increase the stability of the emulsion. In addition, polyethylene glycol is also used as a film coating agent, tablet lubricant, controlled release material, etc.




Principle

The boiling or distilling range of a liquid is the temperature interval,corrected for a pressure of 101.3 kPa within which the liquid,or a specified fraction of the liquid,distills under the conditions specified in the test. The lowerlimit of the range is the temperature indicated by the thermometer when the first drop of condensate leaves the tip of the condenser, and the upper limit is the temperature at which the last drop evaporates from the lowest point in the distillation flask; it may also be the temperature observed when the proportion specified in the individual monograph has been collected.

Applications

Pharmaceutical industry; Petroleum industry

Procedure

1. Install the device and add the sample
2. Plug the thermometer
3. Heat
4. Read and record the temperature

Materials

• Sample Type: liquid
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