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Nitrite (NO2−) and nitrate (NO3−), the major stable oxidation products of nitric oxide (NO), are ubiquitous within biological, food and environmental samples and their biological levels are proposed as indices of cellular NO production. Nitric oxide, biosynthesized from the amino acid l-arginine by a specific neuronal NO synthase, is an important neurotransmitter in various regions of the central nervous system that plays a significant and mysterious role in many biological and physiological functions such as inhibition of platelet aggregation, atherosclerosis, myorelaxant activity, inflammation, blood pressure, immune response and cardiovascular regulation.