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Enceed™ T cell Activation, Human (Gmp) , 4 ml, GenScript (CAT#: STEM-CT-0288-ZJF)

Highlights

Gmp Grade
Ultra Purity
High Recovery

Cat Number: STEM-CT-0288-ZJF

Application: For in vitro activation and expansion of enriched T cell populations or cells from hematological cell populations.

Model: L00935

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Description

The Enceed™ T cell Activation reagent induces T cell activation and expansion in enriched T cells or PBMCs. The Enceed™ T cell Activation reagent is composed of biodegradable matrix-coated nanoparticles conjugated with mouse anti-human CD3 and mouse anti-human CD28 antibodies. The small sized particulate structure of the activation reagent enables its easy removal by media washing or centrifugation.
The recommended titer of 1:200 has been found to achieve efficient stimulation of majority of T cell subsets. For special applications, the optimal stimulation titer should be determined experimentally. Excessive amount of the Enceed™ T cell Activation reagent may result in over-activation of T cells risking activation-induced cell death. During cell expansion using the Enceed™ T cell Activation reagent, the cells take up to 13 days after reagent application to show optimal expansion. Restimulation after 13 days can be performed for longer cultivation. The Enceed™ T cell Activation reagent can be used together with cytokines such as human IL-2, IL-15, and IL-7 for more efficient activation.

Specification

Volume: 4 mL, Up to 2X10^8 T cells
Reactivity: Human
Formulation: Biodegradable matrix-coated nanoparticles conjugated with anti-CD3 and anti-CD28 antibodies supplied in phosphate buffered-saline (PBS), containing Human Serum Albumin (HSA), pH 7.0 - 7.4.
Storage: Store at 2-8 °C. Do not freeze.

Features

Gmp Grade
Ultra Purity
High Recovery
High Viability
Nano-sized
Bio-degradable
Bio-compatible
Cost Efficient

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