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The exogenous promoter and chimeric MERTK coding sequence containing human signal peptide, extracellular domain, transmembrane domain and mouse cytoplasmic domain was inserted to replace part of murine exon 1.
B-hMERTK MC38 cells have the capability to establish tumors in vivo and can be used for efficacy studies.
Common name: B-hMERTK MC38
Aliases: MER, RP38, Tyro12, c-Eyk, c-mer
Organism: Mouse
Tissue types: Colon
Disease: Colon carcinoma
Strain: C57BL/6
Tissue: Colon