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The mouse Pdl1 gene and Ceacam5 gene were replaced by human PD-L1 and CEACAM5 coding sequence in B-hPD-L1 plus/hCEA MC38 cells. Human PD-L1 and CEACAM5 are highly expressed on the surface of B-hPD-L1 plus/hCEA MC38 cells.<br />B-hPD-L1 plus/hCEA MC38 cells have the capability to establish tumors in vivo and can be used for efficacy studies.<br /><br />Common name: B-hPD-L1 plus/hCEA MC38<br />Aliases: <br />PD-L1: CD274, PDCD1L1<br />CEA: CD66e, CEACAM5<br />Organism: Mouse<br />Tissue types: Colon<br />Disease: Colon carcinoma<br />Strain: C57BL/6<br />Tissue: Colon