Application: N-Acetyl-D-Galactosamine Agarose is used for purification of N-acetyl-D-galactosamine specific lectins such as lectin from Glycine max and carbohydrate binding proteins/enzymes.
Lectins are proteins or glycoproteins with at least one non-catalytic domain that specifically and reversibly bind mono- or oligosaccharides. Lectins are important because they have applications in science, medicine, agriculture, pharmaceutical companies, biotechnology and other technologies. Some possible or ongoing applications of lectins are as pesticides, fungicides, anticancer drugs, and antiviral drugs. Lectins are used in the purification of glycoproteins, carbohydrates and glycolipids by affinity chromatography. Lectins also serve as markers for blood types. Therefore, the purification of lectins is very important.
N-Acetyl-D-Galactosamine Sepharose is used for the purification of N-Acetyl-D-Galactose/D-Galactose-specific lectins and carbohydrate-binding proteins/enzymes. Examples of n-acetyl-d-galactosamine-specific lectins include Glycyrrhizin, Dolichos biflorus, Ricin, Peanut, Jacalin and the like.
Specification
Size: 5ml resin Ligand: N-acetyl-D-galactosamine Matrix bead structure: 6 % cross-linked agarose Matrix bead size: 45-160mm Matrix activation: Epoxy Matrix binding to ligand: via –OH groups Spacer arm: 12 atoms Binding capacity: ≥ 6 mg lectin from Glycine max/ ml of resin