Optic Nerve Injury Animal Model (CAT#: STEM-AE-0086-WXH)

Introduction

Optic nerve damage, sometimes called traumatic optic neuropathy, is one of the most common and serious complications following traumatic brain injury. Optic nerve damage is mainly manifested as decreased vision, visual field defects, and abnormal pupillary responses to light. Because optic nerve injury is most common in car accident trauma or head impact injury, many patients may often have craniocerebral or maxillofacial trauma. After many patients are injured, they may also be comatose or unconscious.

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Principle Applications Procedure Materials Notes Related Products

Applications

• Research on clinical treatment of optic nerve injury.
• Research on optic nerve protection.

Procedure

• Animal model of optic nerve injury by blunt orbital trauma:
Indirect optic nerve injury is mainly caused by blunt head trauma, and the impact force is conducted through the orbital bone and concentrated in the optic foramen, resulting in optic nerve injury.
• Animal model of optic nerve injury caused by blunt eyeball trauma:
After the wall of the eyeball is impacted by external force, the retrobulbar optic nerve is displaced and contused.
• Simple animal model of optic nerve injury:
The main methods are cutting injury and crush injury, which directly cause mechanical injury to the optic nerve through external force.

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