Recombinant Human GPC3 Protein, Seafrom (CAT#: STEM-CT-0159-ZJF)

The Recombinant Human GPC3 Protein manufactured by Seafrom is suitable for cancer biology and immunotherapy.
Glypican-3 (GPC3), also known as intestinal protein OCI-5, GTR2-2, and MXR7, belongs to the Glypican family. Glypican-3/GPC-3 is highly expressed in the lungs, liver, and kidneys. It inhibits the dipeptidyl peptidase 4 (DPP4) enzymatic activity. Glypican-3 may play a role in inhibiting/regulating the growth of mesodermal tissues and organs. It might also be involved in regulating the interaction between IGF2 and its receptor, thereby modulating their functions.
The lyophilized form can be stored at 4℃ for 24 months, and the reconstituted liquid can be stored at -20℃ for 6-12 months, avoiding repeated freeze-thaw cycles.

Expression Host: Human HEK293 cells
Source: Human
Synonyms: GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1
Protein Sequence: The DNA sequence encodes human GPC3 (NCBI Reference Sequence: NP_004475.1), expressed with a His tag at the C-terminus.
Molecular Weight: Recombinant human GPC3 protein contains 534 amino acids, with a predicted theoretical molecular weight of 62.4 kD.
Purity: ≥95%, confirmed by SDS-PAGE gel and high-performance liquid chromatography (HPLC) analysis.
Endotoxin: <0.1 EU/μg
Biological Activity (ELISA): Immobilized GPC3 protein (His tag) at a concentration of 1 μg/mL (100 μL/well) can bind to anti-human GPC3 antibody in a linear range of 0.05-5 ng/mL.
Purification Method: Chromatographic purification
Composition: Sterile PBS (pH 7.4) freeze-dried powder containing 6% mannitol.

Optimal Stability
Gmp-Grade Quality
Low Batch-to-Batch Variability
Exceptional Specificity
Robust Bioactivity
Efficient and Reliable Performance

Recombinant Human MSLN Protein, Seafrom
Recombinant Human ROR1 Protein, Seafrom
Recombinant Human LAG-3 Protein (His), Seafrom
Recombinant Human LAG-3 (Fc) Protein, Seafrom