Study of the odorant receptor MOR23 by Patch clamp (CAT#: STEM-PET-0058-WXH)

Introduction

Olfactory receptors (ORs) are G protein-coupled receptors that perform important physiological functions beyond their role as odorant detectors in the olfactory sensory neurons. Olfactory receptors (ORs) form the largest subfamily of GPCRs and were originally postulated to be present in the olfactory epithelium exclusively. Nonetheless, further studies have shown that ORs are much more versatile than previously thought and are now emerging as general chemoreceptors that are found in various tissues, where they perform diverse patterns of regulatory functions.
Mouse OR23 (MOR23) expression is induced during muscle regeneration when muscle cells are extensively fusing and plays a key role in regulating migration and adhesion of muscle cells in vitro, two processes common during tissue repair.