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Tail Suspension Test - Wireless, Bioseb (CAT#: STEM-LEAR-1153-YJL)

Highlights

Fully automatic and operator-independent
Includes 4 types of randomization processes of the animal list
Measurement of up to 6 animals in the same run

Cat Number: STEM-LEAR-1153-YJL

Application: Depression & anxiety<br />Drug screening<br />Basal depressive-like state phenotyping<br />Studies on behavioral abnormalities<br />Behavioral effects of pharmacological compounds relevant to depression<br />Antidepressant efficacy on chronic stress models<br />Sleep and mood disorders<br />Studies on serotonin aspects<br />Acupuncture and dopamine<br />Behavioral effects of genetic manipulations relevant to depression

Model: BIO-TST5

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Description

Tail Suspension Test - Wireless, model BIO-TST5 is manufactured by Bioseb
The tail-suspension test was developed as an alternative to the Porsolt Forced Swimming test, and is based on a similar concept. Mice, suspended by their tail using a piece of tape (a painless method), innately attempt to escape from this adversive situation. However, following failed attempts to escape, they experience a kind of despair and become immobile. The magnitude of immobility is considered to be correlated with the depressive-like state of the subjects and is significantly decreased by antidepressants. The Tail Suspension Test was described in the 80's by Steru & al. and allows for fast evaluation of drugs' (anti-depressants, sedatives) psychotropic effects, making it a classic and painless research test for anxiety and depression.
The power in motion is an additional discriminating calculation that gives an indication of the strength of the mice.

Specification

Dimensions - Overall: 50 x 15 x 30 cm for a set of three cages
Materials: Black and white PVC
Number Of Animals: 1-3 mice if one set of cages is used 1-6 mice if 2 sets of cages are used
Power Supply: 110-230 Volts- 9 volts DC
Sampling Rate: 200 Hz for the sensors 15 images/second for the camera

Features

Fully automatic and operator-independent
Includes 4 types of randomization processes of the animal list
Measurement of up to 6 animals in the same run
Full control of the calibration
High predictability for antidepressant effects in humans
Based on innate behaviours and despair models
Widely used in literature and deeply validated in phenotyping and pharmacology
Simple to set up and use
Replay possible with other parameters
Short-lasting experiment (usually 6 minutes)
Now a wireless instrument with bluetooth connectivity
Optional video recording to adjust the activity threshold

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