UniSil C18 Reversed Phase Bulk Media, UniSil 3-120 C18 (CAT#: STEM-C-3161-ZJF)

UniSil reversed-phase bulk media offer exceptional physical and chemical properties, including uniform particle size, high mechanical strength, strong bonding density, efficient end-capping, high column efficiency, low back pressure, and broad pH tolerance. These characteristics provide significant advantages, such as high chromatographic purification capacity, excellent selectivity, superior resolution, long lifespan, and reduced purification costs.
This reversed-phase chromatography silica gel is available in a wide range of particle sizes and pore sizes, catering to various needs from laboratory analytical high-performance liquid chromatography (UPLC, HPLC) to industrial preparative and process-scale chromatography (Prep-HPLC). It is ideal for separating and purifying organic compounds, natural products, fermentation products, semi-synthetic antibiotics, and protein macromolecules. Customization options are also available for specialized applications.
The C18 phase is the most widely used reversed phase, offering broad versatility for the separation and purification of peptides, antibiotics, natural products, and more.
The C18 AQ phase is optimized for reproducible retention and excellent peak shapes in highly aqueous eluents, including 100% water. It is particularly effective for separating highly polar compounds such as vitamins, organic acids, peptides, proteins, and nucleotides.
The C18 Polar phase is also compatible with 100% aqueous mobile phases, offering a distinct selectivity profile compared to the C18 AQ phase.

Matrix: Silica gel
Particle Size (μm): 3/5/8/10/15/20/30/50
Pore Size (Å): 100, 120, 200, 300
Particle Size CV: ＜5%
Surface Area (m²/g): ~450, ~350, ~200, ~100
Pore Volume (cm³/g): ~0.95
Bulk Density (g/mL): ~0.60, ~0.55, ~0.50, ~0.45
Bonding Phase: Octadecyl
Carbon Content (%): ~16, ~15, ~11, ~7
Max. Pressure (bar): ＜600
Working pH: 2-8
Operational Temperature (℃): 10-60
Storage: After use, the media should be cleaned with salt and sealed with high organic phase (100% ethanol or 100% isopropanol) and stored in a cool and dry place. Keep unopened media in a cool and dry place. The recommended storage temperature is 4 ~ 25℃.

Excellent Physical and Chemical Properties: UniSil reversed-phase bulk media offers uniform particle size, high mechanical strength, high bonding density, good end-capping, high column efficiency, low back pressure, and wide pH tolerance.
High Performance and Low Purification Cost: The media ensures high chromatographic load, good selectivity, resolution, efficiency, long lifespan, and low purification costs.
Versatile Reversed-Phase Options: A full range of reversed-phase media in various particle sizes and pore sizes is available for both analytical (UPLC, HPLC) and preparative (Prep-HPLC, Process HPLC) applications.
Ideal for Organic Compounds and Biotech Applications: Suitable for the separation and purification of organic compounds, natural products, fermentation products, semi-synthetic antibiotics, and protein macromolecules.
C18 Phase - Versatile and Popular: The C18 phase is highly versatile, ideal for separating and purifying peptides, antibiotics, natural products, and more.
C18 AQ Phase - Enhanced Separation in Aqueous Eluents: Designed for reproducible retention and excellent peak shape in highly aqueous eluents, ideal for separating highly polar compounds such as vitamins, organic acids, peptides, proteins, and nucleotides.
C18 Polar Phase - Aqueous Compatibility with Unique Selectivity: Can be used in 100% aqueous mobile phases, with selectivity different from the C18 AQ phase, enhancing separation for specific compounds.

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