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UniSil CN Normal Phase Bulk Media, UniSil 5-120 CN (CAT#: STEM-C-3158-ZJF)

Highlights

Ideal for Polar Compound Separation: Bare UniSil particles are highly effective for the separation and purification of various polar compounds under normal phase conditions, providing good peak shapes.
Successful for Production Purification: UniSil 10 µm normal phases have been particularly successful in the purification of pneumocandin B0 and cyclosporin A.
Variety of Bonded Phases Available: In addition to bare UniSil silica, bonded normal phases such as -Diol, -NH2, and -CN are available for enhanced performance.

Cat Number: STEM-C-3158-ZJF

Application: For the separation, purification, and analysis of complex compounds, including pharmaceuticals, biomolecules, and other high-value substances in research and industrial applications.

Model: UniSil 5-120 CN

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Description

Bare UniSil particles are highly effective for the separation and purification of various polar compounds under normal-phase conditions, delivering consistent peak shapes. The UniSil 10 µm normal-phase media have demonstrated exceptional performance, particularly in the purification processes of pneumocandin B0 and cyclosporin A.
In addition to bare UniSil silica, bonded normal-phase options such as -Diol, -NH2, and -CN are also available. Among these, the Diol phase stands out for its faster equilibrium and enhanced retention capabilities for polar compounds, offering a versatile solution for diverse chromatographic applications.

Specification

Matrix: Silica gel
Particle Size (μm): 1.7/2.0/2.7/3/5/5L/8/10/20/30
Pore Size (Å): 100, 120, 300
Particle Size CV: <5%
Surface Area (m²/g): ~450, ~350, ~100
Pore Volume (cm³/g): ~0.95
Bulk Density (g/mL): ~0.50
Bonding Phase: Cyanide propyl
Carbon Content (%): ~8, ~7, ~3
Max. Pressure (bar): <600
Working pH: 2-8
Operational Temperature (℃): 10-60
Storage: After use, the media should be cleaned with salt and sealed with high organic phase (100% ethanol or 100% isopropanol) and stored in a cool and dry place. Keep unopened media in a cool and dry place. The recommended storage temperature is 4 ~ 25℃.

Features

Ideal for Polar Compound Separation: Bare UniSil particles are highly effective for the separation and purification of various polar compounds under normal phase conditions, providing good peak shapes.
Successful for Production Purification: UniSil 10 µm normal phases have been particularly successful in the purification of pneumocandin B0 and cyclosporin A.
Variety of Bonded Phases Available: In addition to bare UniSil silica, bonded normal phases such as -Diol, -NH2, and -CN are available for enhanced performance.
Improved Retention with Diol Phase: Compared to bare UniSil silica, the Diol phase offers faster equilibrium and better retention for polar compounds, making it ideal for challenging separations.

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