ACQUITY UPLC M-Class System with HDX Technology, Waters Corporation (CAT#: STEM-LE-1967-LC)

The ACQUITY UPLC M-Class System with HDX Technology uses UPLC® separation technology and high-resolution MS to answer important questions about protein conformation changes. The unprecedented system-level design integrates all the steps necessary to accurately, reproducibly, and easily conduct protein conformation studies. The system and its DynamX™ HDX analysis software eliminate the obstacles to routine research of protein conformation changes using high-resolution LC and MS, and make the exchange of hydrogen and deuterium with MS (HDX, HDX MS, HXMS or H/D exchange) a core ability.

Flow Rate:200 nL/min to 100 µL/min
Capacity:768 in Two 384-well plates. or 96 in 2-mL vial holders, plus 4 additional positions for dilution functions or standards
Software:MassLynx ® Software or Standalone Through Console Software
Temperature Range:4 °C to 40 °C

Rapid chromatography separation at 0°C using UPLC® technology
Intuitive interactive DynamX™ HDX data analysis software reduces the time between experiment and answer
Repeat digestion using Waters Enzymate™ BEH pepsin column
Excellent reproducibility and reliability
Integrates with Waters high-resolution MS for optimal retention of deuterium labels
Another level of separation with IMS Technology

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