Analysis of ADAM9 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1884-LGZ)

Introduction

Official Full Name: ADAM metallopeptidase domain 9<br />Also known as: MCMP; MDC9; CORD9; Mltng<br />This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene.