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Official Full Name: BMP/retinoic acid inducible neural specific 3
Also known as: FAM5C; DBCCR1L; DBCCR1L1
This gene is overexpressed in pituitary tumors but underexpressed in squamous cell carcinoma of the tongue, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and this gene has been linked to myocardial infarction. Finally, hypermethylation of this gene may serve as a biomarker for gastric cancer. Two transcript variants of this gene have been found to encode different isoforms.