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Official Full Name: NME/NM23 family member 7
Also known as: NDK7; NDK 7; CFAP67; MN23H7; nm23-H7
This gene encodes a member of the non-metastatically expressed nucleoside diphosphate kinase family. Members of this family are enzymes that catalyze the transfer of phosphate from nucleoside triphosphates to nucleoside diphosphates. The protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. The protein is localized to the centrosome and functions in microtubule organization as part of the γ-tubulin ring complex. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants.