Analysis of cAMP (Human, Mouse, Rat) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0075-LGZ)

Introduction

Cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate are very important second messenger molecules in the process of regulating intracellular energy metabolism by acting on specific protein kinases. Both are abundant in the central nervous system, with AMP involved in higher cortical functions and cyclic guanosine monophosphate involved in phototransduction. Most studies suggest that normal adult lumbar spinal fluid contains 15-30 nmol/L of cAMP, with one study reporting that intraventricular levels may be 2-3 times higher than lumbar levels. cAMP, a derivative of adenosine triphosphate (ATP), mediates cAMP-dependent signal transduction pathways in cells of many different organisms. cAMP participates in the transmembrane regulation mechanism of cell metabolism, differentiation and proliferation, and has good cell inhibition and homeostasis regulation in malignant growth.