Analysis of DNAJB5 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-2045-LGZ)

Introduction

Official Full Name: DnaJ heat shock protein family (Hsp40) member B5<br />Also known as: Hsc40<br />This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone deacetylase 4, serves as a master negative regulator of cardiac hypertrophy.