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Official Full Name: isoleucyl-tRNA synthetase 2, mitochondrial
Also known as: ILERS; CAGSSS
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNAs by their cognate amino acids. Aminoacyl-tRNA synthetases are considered to be among the earliest proteins in evolution due to their central role in linking amino acids and nucleotide triplets contained in tRNAS. Isoleucine-tRNA synthetase exists in two forms, a cytoplasmic form and a mitochondrial form. This gene encodes a mitochondrial isoleucine-tRNA synthetase that belongs to the class I aminoacyl-tRNA synthetase family.