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Official Full Name: ER degradation enhancing alpha-mannosidase like protein 3
Also known as: CDG2V; C1orf22
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER.