Analysis of EML4 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1711-LGZ)

Introduction

Official Full Name: EMAP like 4<br />Also known as: C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120<br />This gene is a member of the echinoderm microtubule-associated protein family. The encoded wd repeat protein may be involved in the formation of microtubules. Aberrant fusion of part of this gene with part of the anaplastic lymphoma receptor tyrosine kinase gene, resulting in an EML4-ALK fusion transcript, is one of the major mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.