Analysis of F5 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0163-LGZ)

Introduction

Also known as: FVL; PCCF; THPH2; RPRGL1
This gene encodes an important cofactor of the coagulation cascade. The factor circulates in the plasma and is converted to the active form by the thrombin-releasing activating peptide during coagulation. This creates heavy and light chains linked together by calcium ions. Activin is a cofactor involved in the activation of coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in autosomal recessive hemorrhagic or autosomal dominant thrombosis, ie, activated protein C resistance.